Regulatory Toxicology And Pharmacology

Application of a next generation risk assessment framework, integrated testing strategy defined approaches and read-across for evaluating the skin sensitization potency: Case studies with 5-hydroxymethylfurfural and 5,5′-oxydimethylenebis (2-furfural

Author: Lin, Ni; Zhang, Jianing; Liu, Ying; Zhang, Fenglan; Wang, Gangli; Yu, Zhenxi; Jin, Hongtao; Lu, Yong

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2026; Vol. 168, Issue , pp. -. DOI: 10.1016/j.yrtph.2026.106056

Association between swimming pool attendance and allergic diseases: An updated systematic review and meta-analysi

Author: Wu, Qingqing; Chen, Xueyu; Ye, Xin; Yan, Yingqi; Ma, Xin; Wang, Yiqian; Liu, Meng; Zhang, Chi; Zhao, Xuezhen; Liu, Yan; Jiao, He; Ji, Long; Yan, Yongheng; Qiao, Jianhong

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2026; Vol. 167, Issue , pp. -. DOI: 10.1016/j.yrtph.2026.106061

Relative quantitative data of cosmetics consumption: An online survey in Guangzhou, Chin

Author: Deng, Junfeng; Wu, Zhen; Lu, Xiaodan; Xian, Xiaoyu; Zheng, Shixiong; Mo, Yunying; Liu, Tianyang; Sun, Siyu; Huang, Shihan; Hong, Ye; Yu, Xingyu; Yijiati, Aliya; Xiao, Chenchen; Zheng, Shuning; Wang, Yue; Yang, Xingfen; Fang, Jihui; He, Zhini

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2026; Vol. 167, Issue , pp. -. DOI: 10.1016/j.yrtph.2026.106058

Nonclinical development of advanced therapies: Best practices for translational and regulatory succes

Author: Zhang, Piyan

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2026; Vol. 166, Issue , pp. -. DOI: 10.1016/j.yrtph.2026.106032

A multi-dimensional comparative study of 505(b)(2) NDAs approved by FDA and Class 2 NDAs approved by NMPA from 2017 to 2023: Uncovering trends, characteristics, and regulation of modified new drug

Author: Fu, Lixia; Dong, Songtao; Xie, Ran; Jia, Guoshu; Zhao, Nan; Xiang, Qian; Ji, Xiwei; Zhao, Xia; Chen, Xiaoyuan; Ma, Lingyue; Cui, Yimin

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2025; Vol. 162, Issue , pp. -. DOI: 10.1016/j.yrtph.2025.105864

Mechanism and marker of voriconazole-induced liver injury: insights from a quantitative systems toxicology approac

Author: Du, Qian; Qiu, Yulan; Yang, Luting; Wang, Chuhui; Teng, Mengmeng; Chen, Jiaojiao; Luo, Yu; Sun, Jinyao; Wang, Taotao; Chen, Siying; Dong, Yalin

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2025; Vol. 162, Issue , pp. -. DOI: 10.1016/j.yrtph.2025.105871

Reproductive and developmental toxicity assessment of HSK21542, a novel peripherally-restricted kappa opioid receptor agonist in rats and rabbit

Author: Gou, Xiaoli; Ye, Qidi; Chen, Bo; Zheng, Yu; Chen, Hongyu; Fan, Litong; Meng, Qingyuan; Zhang, Chen; Lu, Yao; Wang, Ju

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2025; Vol. 159, Issue , pp. -. DOI: 10.1016/j.yrtph.2025.105811

Enhanced pre- and postnatal developmental toxicity (ePPND) study in non-human primates: Necessity, strategic approaches, and critical consideration

Author: Lu, Jing; Dou, Dehu; Wang, Yawen; Shu, Jiaao; Lei, Zhiqi; Huo, Yan; Gong, Xinjiang

Journal: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2025; Vol. 159, Issue , pp. -. DOI: 10.1016/j.yrtph.2025.105814

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

引用次数：26

Assessment of novel tobacco heating product THP1.0. Part 3: Comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions

引用次数：17

Evaluation of the safety profile of an electronic vapour product used for two years by smokers in a real-life setting

引用次数：14

Human relevance of rodent liver tumors: Key insights from a Toxicology Forum workshop on nongenotoxic modes of action

引用次数：13

Developing OECD test guidelines for regulatory testing of nanomaterials to ensure mutual acceptance of test data

引用次数：11

Oxidative stress responses in human bronchial epithelial cells exposed to cigarette smoke and vapor from tobacco- and nicotine-containing products

引用次数：10

Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides

引用次数：9

Reflections on the progress towards non-animal methods for acute toxicity testing of chemicals

引用次数：8

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine

引用次数：8

A monitoring survey and dietary risk assessment for pesticide residues on peaches in China

引用次数：8